NAD+ and the Myers' Cocktail are the two most-asked-about drips on a wellness menu. They solve different problems, on different timelines, at different price points. This is a clear side-by-side comparison to help you pick the right one.
Quick summary
| | NAD+ IV | Myers' Cocktail | | --- | --- | --- | | What it does | Restores cellular NAD+ for energy and cognitive function | Broad-spectrum vitamin/mineral restoration | | Primary effect | Sharp mental clarity, sustained energy | Gentle, reliable wellness maintenance | | Effect arc | Builds over 24–72 hours; lasts days | Felt within 30 min; lasts 2–4 days | | Session length | 90 min – 3 hrs (must drip slowly) | 30–45 min | | Typical cost | $349 – $599 per session | $149 – $199 per session | | Best for | Adults 45+, executives, longevity focus | First-time IV clients, maintenance, immune support | | Cadence | Loading course + monthly maintenance | Weekly to monthly as needed | | In our menu | Executive Edge (maintenance dose) | The Reset |
What each one actually does
NAD+ IV
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme every cell in your body uses to generate energy and repair DNA. Levels decline substantially with age — most people have roughly half the NAD+ at 60 that they had at 30. IV infusion restores cellular NAD+ directly, bypassing the digestive tract.
The effect is not gentle. Clients report mental clarity, improved focus, and sustained energy that builds over 24–72 hours. It is specifically designed for:
- Adults over 45 who want to counter age-related cognitive and cellular decline.
- Executives managing chronic high cognitive load.
- Athletes layering recovery with cognitive performance.
- Anyone with a family history of neurodegenerative concerns.
The tradeoff is session length and cost. NAD+ must drip slowly — too fast and it produces chest pressure and warmth. A therapeutic dose runs 90 minutes to three hours, and the cost reflects both the compound and the clinical time.
For most people, NAD+ is a series, not a one-off. A typical loading protocol is 4–6 infusions over 2–4 weeks, with maintenance every 4–8 weeks after. Single infusions produce measurably less dramatic effects.
Myers' Cocktail
The Myers' Cocktail was developed by Dr. John Myers in Baltimore in the 1960s. It is the original IV wellness formulation and the direct ancestor of every modern drip menu. The formula is a balanced blend of:
- Magnesium for muscle relaxation and stress response.
- Calcium for nerve and muscle function.
- B-complex vitamins for energy metabolism.
- Vitamin C for antioxidant and immune support.
No single ingredient dominates. The synergy between them is the point — which is also why the effect is steady and reliable rather than dramatic. Most clients feel more alert and hydrated within 30 minutes, with full effects lasting 2–4 days.
Myers' is specifically designed for:
- First-time IV clients who want a gentle entry point.
- Routine maintenance and general wellness.
- Post-illness recovery and mild immune support.
- Anyone who values broad-spectrum restoration over targeted intervention.
Which one should you book?
Book NAD+ if you are 45 or older, dealing with cognitive fatigue, running a longevity protocol, or committing to a course of infusions rather than a one-off. It is specifically useful before demanding work periods or during post-burnout recovery.
Book the Myers' Cocktail if you are new to IV therapy, want a standing wellness appointment, or are looking for reliable broad-spectrum support rather than a targeted intervention. It is also the better pick for pre-event hydration, mild illness recovery, and post-travel reset.
Book both over time if you want the full wellness stack. Many of our clients do a Myers'-style drip (The Reset) on a weekly or bi-weekly cadence and layer NAD+ (Executive Edge) quarterly.
Both drips on the LuxeFlow menu
- The Reset — our modern Myers-style baseline protocol.
- Executive Edge — NAD+ in a cognitive-first formulation, at a maintenance dose suitable for regular use.
Full pricing and session-length details are on the pricing page. If you are unsure, book The Reset first — it is the lower-risk entry point for most people, and you can step up to Executive Edge on a subsequent visit.
Related reading
- NAD+ IV Therapy: Benefits, Cost, and Who It Is For — deep dive on the NAD+ side specifically.
- Myers' Cocktail: The Original Wellness Drip — history and formulation details.
- Glutathione IV: Benefits, Cost, Timing — a common add-on to both drips.